MLB scores, schedule and odds: Monday, February 22, 2027

The MLB schedule for Monday, February 22, 2027 has 16 games.

First up: Mets at Astros at 12:00 AM ET.

• New York Mets at Houston Astros — Mon, Feb 22 12:00 AM ET · CACTI Park of the Palm Beaches, Palm Beach
• St. Louis Cardinals at Boston Red Sox — Mon, Feb 22 12:00 AM ET · JetBlue Park at Fenway South, Fort Myers
• Tampa Bay Rays at Atlanta Braves — Mon, Feb 22 12:00 AM ET · CoolToday Park, North Port
• Washington Nationals at Miami Marlins — Mon, Feb 22 12:00 AM ET · Roger Dean Chevrolet Stadium, Jupiter
• Chicago Cubs at Arizona Diamondbacks — Mon, Feb 22 12:00 AM ET · Salt River Fields at Talking Stick, Scottsdale
• Kansas City Royals at Cincinnati Reds — Mon, Feb 22 12:00 AM ET · Goodyear Ballpark, Goodyear
• Los Angeles Dodgers at Los Angeles Angels — Mon, Feb 22 12:00 AM ET · Tempe Diablo Stadium, Tempe
• Texas Rangers at Milwaukee Brewers — Mon, Feb 22 12:00 AM ET · American Family Fields of Phoenix, Phoenix
• Boston Red Sox at Baltimore Orioles — Mon, Feb 22 1:05 PM ET · Ed Smith Stadium, Sarasota
• Philadelphia Phillies at Minnesota Twins — Mon, Feb 22 1:05 PM ET · Lee Health Sports Complex, Fort Myers
• Pittsburgh Pirates at Toronto Blue Jays — Mon, Feb 22 1:07 PM ET · TD Ballpark, Dunedin
• Cleveland Guardians at Texas Rangers — Mon, Feb 22 3:05 PM ET · Surprise Stadium, Surprise
• Colorado Rockies at Athletics — Mon, Feb 22 3:05 PM ET · Hohokam Stadium, Mesa
• Seattle Mariners at Chicago White Sox — Mon, Feb 22 3:05 PM ET · Camelback Ranch - Glendale, Phoenix
• San Francisco Giants at San Diego Padres — Mon, Feb 22 3:10 PM ET · Peoria Stadium, Peoria
• Detroit Tigers at New York Yankees — Mon, Feb 22 6:35 PM ET · George M. Steinbrenner Field, Tampa