MLB scores, schedule and odds: Friday, April 16, 2027

The MLB schedule for Friday, April 16, 2027 has 15 games.

First up: Athletics at Blue Jays at 12:00 AM ET on MLB.TV.

• Athletics at Toronto Blue Jays — Fri, Apr 16 12:00 AM ET · Rogers Centre, Toronto
• Chicago Cubs at Los Angeles Dodgers — Fri, Apr 16 12:00 AM ET · Dodger Stadium, Los Angeles
• Cincinnati Reds at Pittsburgh Pirates — Fri, Apr 16 12:00 AM ET · PNC Park, Pittsburgh
• Cleveland Guardians at Boston Red Sox — Fri, Apr 16 12:00 AM ET · Fenway Park, Boston
• Houston Astros at Seattle Mariners — Fri, Apr 16 12:00 AM ET · T-Mobile Park, Seattle
• San Diego Padres at Arizona Diamondbacks — Fri, Apr 16 12:00 AM ET · Chase Field, Phoenix
• San Francisco Giants at Chicago White Sox — Fri, Apr 16 12:00 AM ET · Rate Field, Chicago
• Baltimore Orioles at Los Angeles Angels — Fri, Apr 16 6:38 PM ET · Angel Stadium, Anaheim
• Milwaukee Brewers at Philadelphia Phillies — Fri, Apr 16 6:40 PM ET · Citizens Bank Park, Philadelphia
• Washington Nationals at New York Yankees — Fri, Apr 16 7:05 PM ET · Yankee Stadium, Bronx
• Miami Marlins at Atlanta Braves — Fri, Apr 16 7:15 PM ET · Truist Park, Atlanta
• Detroit Tigers at Minnesota Twins — Fri, Apr 16 7:40 PM ET · Target Field, Minneapolis
• Tampa Bay Rays at Kansas City Royals — Fri, Apr 16 7:40 PM ET · Kauffman Stadium, Kansas City
• St. Louis Cardinals at Texas Rangers — Fri, Apr 16 8:10 PM ET · Globe Life Field, Arlington
• New York Mets at Colorado Rockies — Fri, Apr 16 8:40 PM ET · Coors Field, Denver