Serie A scores, schedule and odds: Saturday, November 21, 2026

The Serie A schedule for Saturday, November 21, 2026 has 4 games.

First up: Lecce at Lazio at 9:00 AM ET on Paramount+.

• Lecce at Lazio — Sat, Nov 21 9:00 AM ET · Olimpico, Roma · Line LAZ -295, total 2.5
• Cagliari at Como — Sat, Nov 21 9:00 AM ET · Giuseppe Sinigaglia, Como · Line COMO -350, total 3.5
• AS Roma at Parma — Sat, Nov 21 12:00 PM ET · Ennio Tardini, Parma · Line ROMA -360, total 3.5
• Torino at Napoli — Sat, Nov 21 2:45 PM ET · Stadio Diego Armando Maradona, Napoli · Line NAP -225, total 2.5